Use that is common
Particularly and actively inhibits aggregation of platelets (clotting) and dilatates coronary vessels. Plavix is used to diminish the risk of heart attacks and strokes caused by blood clots is increased in patients with a recent history of peripheral vascular disease and stroke, heart attach. It truly is used to prevent ischemic ailments like myocardial infarction, stroke, thrombosis of others and peripheral arteries.
Plavix should be taken once a day with or without food.
Precautions
As Plavix belongs to 'blood thinners' avoid taking it with aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) if your physician failed to urge one to do it. Contact your physician if you discovered if you cough up blood or that you've bloody or black stools, vomit that's similar to coffee grounds.
Contraindications
Hypersensitivity, ulcer of stomach or duodenum, serious liver failure, acute bleeding, ulcerous colitis, tuberculosis and other diseases predisposing to bleeding, pregnancy, breastfeeding, neonatal period. Caution should be exercised in patients with moderate liver of kidney failure.
Side effect that is potential
Bleeding in bowels or belly, hemorrhagic stroke, neuropenia, thrombocytopenia, abdominal pain, dyspepsia, gastritis, constipation, ulcers in gastrointestinal tract, diarrhea, allergy.
Drug interaction
Missed dose
Never take a double dose of the medication. When it is almost time of the next dose simply skip the portion that is missed and continue to take the medication in accordance with the schedule.
Overdose
Symptoms of an overdose are vomiting, feeling exhausted or shortness of breath, and signs of blood in vomit, diarrhea, rush, itching or your feces.
Storage
Shop Plavix pills and capsules should be kept at room temperature between 15-30 C (59-86 F).
Disclaimer
We provide just general information about drugs which will not cover precautions, drug integrations that are potential, or all directions. Tips at the website cannot be used for self-treatment and self diagnosis. Any specific instructions for a particular patient should be agreed with doctor or your healthcare advisor responsible for the case. We disclaim reliability of this information and blunders it could comprise. We are not responsible for any direct, indirect, special or other indirect damage as an outcome of any use of the information with this site and also for effects of self-treatment.
Plavix 75 mg. round, pink, imprinted with 75, 1171. What are the possible side effects of clopidogrel Plavix. Get emergency medical help if you have any of these.
Dosage Forms and Strengths. 75 mg tablets: Pink, round, biconvex, film-coated tablets debossed with 75 on one side and 1171 on the other; 300 mg tablets: Pink.
PLAVIX 75 MG TABLET. Identification color No data. shape No data. imprint No data. This medicine is a pink, round, film-coated tablet imprinted with 75 and 1171.
Plavix clopidogrel bisulfate is a thienopyridine class
inhibitor of P2Y12ADP platelet receptors. Chemically it is methyl - S -α- 2-chlorophenyl -6,7-dihydrothieno 3,2-c pyridine-5 4H -acetate
sulfate 1:1. The empirical formula of clopidogrel bisulfate is C16H16ClNO2S H2SO4
and its molecular weight is 419.9.
The structural formula is as follows:
Clopidogrel bisulfate is a white to off-white powder. It
is practically insoluble in water at neutral pH but freely soluble at pH 1. It
also dissolves freely in methanol, dissolves sparingly in methylene chloride,
and is practically insoluble in ethyl ether. It has a specific optical rotation
Plavix for oral administration is provided as either
pink, round, biconvex, debossed, film-coated tablets containing 97.875 mg of
clopidogrel bisulfate which is the molar equivalent of 75 mg of clopidogrel
base or pink, oblong, debossed film-coated tablets containing 391.5 mg of
clopidogrel bisulfate which is the molar equivalent of 300 mg of clopidogrel
Each tablet contains hydrogenated castor oil,
hydroxypropylcellulose, mannitol, microcrystalline cellulose and polyethylene
glycol 6000 as inactive ingredients. The pink film coating contains ferric oxide,
hypromellose 2910, lactose monohydrate, titanium dioxide and triacetin. The
tablets are polished with Carnauba wax.
What are the possible side effects of clopidogrel Plavix.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using clopidogrel and call your doctor at once if you have any of these serious side effects:nosebleed or other bleeding that will not stop;bloody or tarry stools, blood in your urine;coughing up blood or vomit that looks like coffee grounds;chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;sudden numbness or
Read All Potential Side Effects and See Pictures of Plavix
Pharmacist reviewed on 8/17/2015
Prescribing Document Revised: December 2013
This monograph has been modified to include the generic and brand name in many instances.
Plavix 75mg tablets. Company Details. SANOFI 1 Onslow Street once at the start of treatment. Then, the recommended dose is one 75 mg tablet of Plavix per day as.
Posology Adults and older people. Clopidogrel should be given as a single daily dose of 75 mg. In patients suffering from acute coronary syndrome: Non-ST.
Plavix (Clopidogrel Bisulfate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions - Prescribing Information at RxList
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research CDER – November 2009
Reduced effectiveness due to impaired CYP2C19 function
The inhibition of platelet aggregation by clopidogrel is entirely due to an active metabolite. Clopidogrel is metabolized to this active metabolite in part by CYP2C19. This metabolism can be impaired by genetic variations in CYP2C19 and by concomitant medications that interfere with CYP2C19. Avoid use of Plavix in patients with impaired CYP2C19 function due to known genetic variation or due to drugs that inhibit CYP2C19 activity.
Genetic variations: Patients with genetically reduced CYP2C19 function have diminished antiplatelet responses and generally exhibit higher cardiovascular event rates following myocardial infarction than do patients with normal CYP2C19 function.
Drug interactions: Co-administration of Plavix with omeprazole, a proton pump inhibitor that is an inhibitor of CYP2C19, reduces the pharmacological activity of Plavix if given concomitantly or if given 12 hours apart. There is no evidence that other drugs that reduce stomach acid, such as most H2 blockers except cimetidine, which is a CYP2C19 inhibitor or antacids interfere with the antiplatelet activity of clopidogrel.
subsection was reworded and reordered
Omeprazole: In a crossover clinical study, 72 healthy subjects were administered Plavix 300-mg loading dose followed by 75 mg/day alone and with omeprazole 80 mg at the same time as Plavix for 5 days.
- Aug 31, 2014 Plavix clopidogrel bisulfate 75 mg tablet. Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research CDER.
- Learn about the prescription medication Plavix Clopidogrel Bisulfate, drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling.